{"id":3308,"date":"2024-09-25T22:18:34","date_gmt":"2024-09-25T22:18:34","guid":{"rendered":"https:\/\/von-steineck.de\/?p=3308"},"modified":"2024-10-14T18:03:41","modified_gmt":"2024-10-14T18:03:41","slug":"information-zum-vererblichem-congenitalen-megaoesophagus-cim-2","status":"publish","type":"post","link":"https:\/\/von-steineck.de\/en\/information-zum-vererblichem-congenitalen-megaoesophagus-cim-2","title":{"rendered":"Information on Hereditary Congenital Megaesophagus (CIM)"},"content":{"rendered":"<div data-elementor-type=\"wp-post\" data-elementor-id=\"3308\" class=\"elementor elementor-3308\" data-elementor-post-type=\"post\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-1b086d8 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"1b086d8\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-5116721\" data-id=\"5116721\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-0a6eb97 elementor-widget__width-initial elementor-widget elementor-widget-post-info\" data-id=\"0a6eb97\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"post-info.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<ul class=\"elementor-icon-list-items elementor-post-info\">\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item elementor-repeater-item-88d0fef\" itemprop=\"author\">\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t\t<i aria-hidden=\"true\" class=\"far fa-user-circle\"><\/i>\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text elementor-post-info__item elementor-post-info__item--type-author\">\n\t\t\t\t\t\t\t\t\t\tMartina\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t<li class=\"elementor-icon-list-item elementor-repeater-item-7f39d87\" itemprop=\"datePublished\">\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t\t<i aria-hidden=\"true\" class=\"fas fa-calendar-alt\"><\/i>\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text elementor-post-info__item elementor-post-info__item--type-date\">\n\t\t\t\t\t\t\t\t\t\t<time>September 25, 2024<\/time>\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t<\/ul>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-0115ef5 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"0115ef5\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-0a81f44\" data-id=\"0a81f44\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-5e9f41e elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"5e9f41e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-6857370 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"6857370\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-bbfd629\" data-id=\"bbfd629\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-dc794df elementor-widget elementor-widget-text-editor\" data-id=\"dc794df\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"font-size: 12pt;\">Since we also lost puppies in our last litter due to congenital megaesophagus, I would like to emphasize once again the importance of thoroughly researching the test results of the parents in your planned breeding. Even a mating between two carriers (CIM\/N &amp; CIM\/N) carries a high risk of producing affected puppies. Since breeders knowingly mate parents who are both <\/span>CIM\/CIM sind und Experimente auf Kosten der Welpen treiben, habe ich mich entschlossen nochmal hier aufzukl\u00e4ren, weil ich es einfach nicht fassen kann, das solchen Z\u00fcchtern, ein Welpenleben scheissegal ist!<\/p><div dir=\"ltr\">\u00a0<\/div><div dir=\"ltr\">Congenital megaesophagus (CIM)<\/div><div dir=\"ltr\">\u00a0<\/div><div dir=\"ltr\">Congenital megaesophagus (CIM) is a motility disorder of the esophagus that prevents the normal transport of food to the stomach due to reduced peristaltic activity and dilation. Affected dogs exhibit regurgitation of food and water, coughing, and complications such as aspiration pneumonia, excessive salivation, mild to moderate cachexia, and crackles or wheezing. A normal esophagus contracts to allow food to pass into the stomach. In affected animals, it does not contract normally, leading to food retention and dilation. The frequency of regurgitation can vary from just one episode every few days to several episodes per day. In affected puppies, the first clinical signs appear at 3\u20134 weeks of age.<\/div><div dir=\"ltr\">\u00a0<\/div><div dir=\"ltr\">Inheritance: autosomal recessive<\/div><div dir=\"ltr\">\u00a0<\/div><div dir=\"ltr\">Mutation: MCHR2 gene<\/div><div dir=\"ltr\">\u00a0<\/div><div dir=\"ltr\">Genetic Test: We can identify carriers of the disease at any age. PCR is a precise testing method that allows us to distinguish between affected, carrier, and healthy animals. The test can be performed at any age.<\/div><div dir=\"ltr\">\u00a0<\/div><div dir=\"ltr\">Healthy animals: CIM N\/N<\/div><div dir=\"ltr\">Organizer: CIM \/ N\/CIM<\/div><div dir=\"ltr\">Affected animals: CIM CIM\/CIM<\/div><div dir=\"ltr\">\u00a0<\/div><div dir=\"ltr\">Most breeders just say, \u201cI\u2019ve never had that before\u2014is there even a test for it?\u201d Or, \u201cOther breeders don\u2019t test either\u2026\u201d Then there are those who do test but keep everything secret, which makes me wonder why they don\u2019t keep the results of the MDR1 or dwarfism tests secret?! And the rest just hope for healthy puppies no matter what the parents\u2019 results are, but that\u2019s how they keep spreading this disease further and further\u2026<\/div><div dir=\"ltr\">\u00a0<\/div><div dir=\"ltr\">Of course, it\u2019s time-consuming and not exactly cheap to test both the parents and the puppies from a litter, but I think it\u2019s only beneficial for the future and the preservation of a high-quality German Shepherd breeding program.<\/div><div dir=\"ltr\">\u00a0<\/div><div dir=\"ltr\">There are now a total of 15 breed-specific tests for German Shepherds offered by various laboratories around the world. Reputable breeders should at least have these tests performed voluntarily, even if the breed clubs do not require them.<\/div><div dir=\"ltr\">\u00a0<\/div><p><span style=\"font-size: 18pt;\">\u00a0<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-abf0a46 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"abf0a46\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-e5cf97d\" data-id=\"e5cf97d\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-4eb3325 elementor-widget elementor-widget-image\" data-id=\"4eb3325\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/von-steineck.de\/wp-content\/uploads\/2021\/07\/image0-4.jpeg\" data-elementor-open-lightbox=\"yes\" data-elementor-lightbox-title=\"image0 (4)\" data-e-action-hash=\"#elementor-action%3Aaction%3Dlightbox%26settings%3DeyJpZCI6MzEyOSwidXJsIjoiaHR0cHM6XC9cL3Zvbi1zdGVpbmVjay5kZVwvd3AtY29udGVudFwvdXBsb2Fkc1wvMjAyMVwvMDdcL2ltYWdlMC00LmpwZWcifQ%3D%3D\">\n\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"300\" height=\"300\" src=\"https:\/\/von-steineck.de\/wp-content\/uploads\/2021\/07\/image0-4-300x300.jpeg\" class=\"attachment-ashe-list-thumbnail size-ashe-list-thumbnail wp-image-3129\" alt=\"\" srcset=\"https:\/\/von-steineck.de\/wp-content\/uploads\/2021\/07\/image0-4-300x300.jpeg 300w, https:\/\/von-steineck.de\/wp-content\/uploads\/2021\/07\/image0-4-150x150.jpeg 150w, https:\/\/von-steineck.de\/wp-content\/uploads\/2021\/07\/image0-4-75x75.jpeg 75w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/>\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-64c4eca elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"64c4eca\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-b823f09\" data-id=\"b823f09\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-cfa9e8d elementor-widget elementor-widget-text-editor\" data-id=\"cfa9e8d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div dir=\"ltr\"><div dir=\"ltr\" style=\"text-align: left;\">At around 4 weeks of age, an X-ray with contrast dye performed at our veterinary clinic revealed that this sweet little baby had congenital megaesophagus, and unfortunately, we had to euthanize the baby.\u00a0<\/div><\/div><div dir=\"ltr\">\u00a0<\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-a002908 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"a002908\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-3c2cc93\" data-id=\"3c2cc93\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-24b4602 elementor-widget elementor-widget-image\" data-id=\"24b4602\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/von-steineck.de\/wp-content\/uploads\/2024\/09\/image0-5.jpeg\" data-elementor-open-lightbox=\"yes\" data-elementor-lightbox-title=\"image0 (5)\" data-e-action-hash=\"#elementor-action%3Aaction%3Dlightbox%26settings%3DeyJpZCI6MzA4MiwidXJsIjoiaHR0cHM6XC9cL3Zvbi1zdGVpbmVjay5kZVwvd3AtY29udGVudFwvdXBsb2Fkc1wvMjAyNFwvMDlcL2ltYWdlMC01LmpwZWcifQ%3D%3D\">\n\t\t\t\t\t\t\t<img decoding=\"async\" width=\"500\" height=\"330\" src=\"https:\/\/von-steineck.de\/wp-content\/uploads\/2024\/09\/image0-5-500x330.jpeg\" class=\"attachment-ashe-grid-thumbnail size-ashe-grid-thumbnail wp-image-3082\" alt=\"\" \/>\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"<p>Da wir bei unserem letzten Wurf auch Welpen verloren haben durch den angeborenen Mega\u00f6sophagus, m\u00f6chte ich nochmals drauf hinweisen, sich gr\u00fcndlich zu informieren, welche Testergebnisse die Eltern der geplanten Wurfplanungen haben. Schon eine Tr\u00e4ger Verpaarung CIM\/N &#038; CIM\/N ist ein hohes Risiko um kranke Welpen zu bekommen. Da Z\u00fcchter wissentlich mit Eltern verpaaren die beide<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"elementor_theme","format":"standard","meta":{"ngg_post_thumbnail":0,"footnotes":""},"categories":[98],"tags":[],"class_list":["post-3308","post","type-post","status-publish","format-standard","hentry","category-hundekrankheiten"],"acf":[],"_links":{"self":[{"href":"https:\/\/von-steineck.de\/en\/wp-json\/wp\/v2\/posts\/3308","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/von-steineck.de\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/von-steineck.de\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/von-steineck.de\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/von-steineck.de\/en\/wp-json\/wp\/v2\/comments?post=3308"}],"version-history":[{"count":78,"href":"https:\/\/von-steineck.de\/en\/wp-json\/wp\/v2\/posts\/3308\/revisions"}],"predecessor-version":[{"id":3781,"href":"https:\/\/von-steineck.de\/en\/wp-json\/wp\/v2\/posts\/3308\/revisions\/3781"}],"wp:attachment":[{"href":"https:\/\/von-steineck.de\/en\/wp-json\/wp\/v2\/media?parent=3308"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/von-steineck.de\/en\/wp-json\/wp\/v2\/categories?post=3308"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/von-steineck.de\/en\/wp-json\/wp\/v2\/tags?post=3308"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}